- 品牌:禾午生物
- 产地:国产
- 型号:20ug/100ug/1mg
- 货号:AA10198
- 发布日期: 2022-04-21
- 更新日期: 2024-10-08
产地 | 国产 |
品牌 | 禾午生物 |
货号 | AA10198 |
用途 | 仅供科研 |
包装规格 | 20ug/100ug/1mg |
纯度 | 85% |
是否进口 | 否 |
名称:Recombinant Human Interleukin-36 receptor antagonist protein(IL36RN)
产品货号:AA10198
规格:20ug 100ug 1mg
产品详情
纯度:Greater than 95% as determined by SDS-PAGE.
内毒素:Less than 1.0 EU/μg as determined by LAL method.
生物活性:The ED50 as determined by its ability to inhibit IL-36 alpha, IL-36 beta or IL-36 gamma -induced IL-8 secretion in A431 human epithelial carcinoma cells is less than 500 ng/ml in the presence of 10 ng/mL of recombinant human IL-36 beta.
基因名:IL36RN
Uniprot No.:Q9UBH0
别名:AI413231; Family of interleukin 1 delta; FIL1; FIL1 delta; FIL1(DELTA); FIL1D; Fil1delta; I36RA_HUMAN; IL 1 delta; IL 1 related protein 3; IL 1F5 (IL 1HY1, FIL1 delta, IL 1RP3, IL 1L1, IL 1 delta); Il 1h3; IL 1HY1; IL 1L1; IL 1ra homolog; IL 1ra homolog, IL1F5 (Canonical product IL 1F5a); IL 1RP3; IL-1 delta; IL-1-related protein 3; IL-1F5; IL-1HY1; IL-1L1; IL-1ra homolog 1; IL-1RP3; IL1F5; IL1HY1; IL1L1; IL1RP3; IL36RA; IL36RN; Interleukin 1 delta; Interleukin 1 family member 5 (delta); Interleukin 1 family member 5; Interleukin 1 HY1; Interleukin 1 like protein 1; Interleukin 1 receptor antagonist homolog 1; Interleukin 36 receptor antagonist; Interleukin-1 delta; Interleukin-1 family member 5; Interleukin-1 HY1; Interleukin-1 receptor antagonist homolog 1; Interleukin-1-like protein 1; Interleukin-36 receptor antagonist protein; MGC29840; PSORP; RP23-176J12.6
种属:Homo sapiens (Human)
蛋白长度:Full Length
来源:E.coli
分子量:16.9 kDa
表达区域:1-155aa
蛋白标签:Tag-Free
产品提供形式:Liquid or Lyophilized powder
功能:通过结合到受体IL1RL2并阻止其与辅受体IL1RAP的关联来抑制白介素-36 (IL36A,IL36B和IL36G)的活性。部分IL-36信号系统,被认为存在于上皮屏障中并参与局部反应;类似于IL-1系统,它与IL-1共享共同受体。建议在中发挥作用。可能参与对真菌病原体的先天免疫反应,如烟曲霉。可能通过招募SIGIRR来激活信号通路。
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蛋白表达与纯化服务 纯化的蛋白经过ELISA,Western-blot,或者其它生物活性验证标签切除测序报告
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